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Scientific misconduct from the perspective of research coordinators: a national survey
  1. Erica R Pryor1,
  2. Barbara Habermann1,
  3. Marion E Broome2
  1. 1School of Nursing, University of Alabama at Birmingham, Birmingham, Alabama, USA
  2. 2School of Nursing, Indiana University, Indianapolis, Indiana, USA
  1. Correspondence to:
 Dr E R Pryor
 School of Nursing, University of Alabama at Birmingham, 1530, 3rd Avenue South, NB 235, Birmingham, AL 35294-1210, USA; erpphd{at}


Objective: To report results from a national survey of coordinators and managers of clinical research studies in the US on their perceptions of and experiences with scientific misconduct.

Methods: Data were collected using the Scientific Misconduct Questionnaire-Revised. Eligible responses were received from 1645 of 5302 (31%) surveys sent to members of the Association of Clinical Research Professionals and to subscribers of Research Practitioner, published by the Center for Clinical Research Practice, between February 2004 and January 2005.

Findings: Overall, the perceived frequency of misconduct was low. Differences were noted between workplaces with regard to perceived pressures on investigators and research coordinators, and on the effectiveness of the regulatory environment in reducing misconduct. First-hand experience with an incident of misconduct was reported by 18% of respondents. Those with first-hand knowledge of misconduct were more likely to report working in an academic medical setting, and to report that a typical research coordinator would probably do nothing if aware that a principal investigator or research staff member was involved in an incident of misconduct.

Conclusion: These findings expand the knowledge on scientific misconduct by adding new information from the perspective of research coordinators. The findings provide some data supporting the influence of workplace climate on misconduct and also on the perceived effectiveness of institutional policies to reduce scientific misconduct.

  • ACRP, Association of Clinical Research Professionals
  • ORI, Office of Research Integrity
  • PI, principal investigator
  • SMQ-R, Scientific Misconduct Questionnaire-Revised

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  • Funding: The research that supported the development of this paper was funded by the National Institute for Nursing Research, NIH R01 NR008802.

  • Competing interests: None.

  • Ethics approval: The survey protocol was reviewed and approved by the institutional review board for human subjects use at the University of Alabama at Birmingham, Birmingham, Alabama, USA.

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