Article Text

Download PDFPDF
Genetically selected baby free of inherited predisposition to early-onset Alzheimer’s disease
  1. M Spriggs
  1. Ethics Unit, Murdoch Childrens Research Institute, Royal Childrens Hospital, Flemington Road, Parkville, Victoria, 3052, Australia;

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Is it right to use pre-implantation genetic diagnosis to select an embryo free of the gene for early-onset Alzheimer’s disease?

    A 30 year old woman with the gene for early-onset Alzheimer’s disease, who seems certain to develop the disease by the time she is 40, has used IVF and preimplantation genetic diagnosis to select an embryo that is free of the mutant gene. The woman, a geneticist, has given birth to a mutation-free child. This marks the first time that preimplantation genetic diagnosis has been used to “weed out” an embryo with the defect.1–3

    Early-onset Alzheimer’s is an inherited, incurable disease striking people …

    View Full Text

    Other content recommended for you