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In the January 4 issue of the New England Journal of Medicine three articles appeared on the unapproved use of Misoprostol (Cytotec), which raise an interesting ethical question. The synthetic prostaglandin analogue, Misoprostol, has been successfully used by obstetricians and gynaecologists for a number of years for the induction of a medical abortion in the first or second trimester, for the induction of labour, and for the prevention of postpartum haemorrhages.1 Strangely enough the pharmaceutical company which produces and markets the drug, Searle, …