Biosecurity and the review and publication of dual-use research of concern

D Patrone, D Resnik, L Chin - Biosecurity and Bioterrorism …, 2012 - liebertpub.com
Dual-use research of concern (DURC) is scientific research with significant potential for
generating information that could be used to harm national security, the public health, or the …

[HTML][HTML] Cell Immortalization: In Vivo Molecular Bases and In Vitro Techniques for Obtention

JC de Bardet, CR Cardentey, BL González, D Patrone… - BioTech, 2023 - mdpi.com
Somatic human cells can divide a finite number of times, a phenomenon known as the
Hayflick limit. It is based on the progressive erosion of the telomeric ends each time the cell …

[HTML][HTML] Pandemic ventilator rationing and appeals processes

D Patrone, D Resnik - Health Care Analysis, 2011 - Springer
In a severe influenza pandemic, hospitals will likely experience serious and widespread
shortages of patient pulmonary ventilators and of staff qualified to operate them. Deciding …

Research misconduct policies of social science journals and impact factor

DB Resnik, D Patrone, S Peddada - Accountability in research, 2010 - Taylor & Francis
In this study we gathered data on the misconduct policies of social science journals and
combined it with the data from our previous study on journal misconduct policies, which did …

Disfigured anatomies and imperfect analogies: body integrity identity disorder and the supposed right to self-demanded amputation of healthy body parts

D Patrone - Journal of medical ethics, 2009 - jme.bmj.com
Patients with the controversial diagnosis of body integrity identity disorder (BIID) report an
emotional discomfort with having a body part (usually a limb) that they feel should not be …

Visual goal-directed meta-imitation learning

…, DA Handelman, CR Ratto, D Patrone… - Proceedings of the …, 2022 - openaccess.thecvf.com
The goal of meta-learning is to generalize to new tasks and goals as quickly as possible.
Ideally, we would like approaches that generalize to new goals and tasks on the first attempt …

[HTML][HTML] Current Progress in the Chemoenzymatic Synthesis of Natural Products

EP Vanable, LG Habgood, JD Patrone - Molecules, 2022 - mdpi.com
Natural products, with their array of structural complexity, diversity, and biological activity,
have inspired generations of chemists and driven the advancement of techniques in their …

[HTML][HTML] Optimization of peripheral blood mononuclear cell extraction from small volume of blood samples: potential implications for children-related diseases

D Patrone, N Alessio, N Antonucci, AL Brigida… - Methods and …, 2022 - mdpi.com
Managing medical procedures for children with problematic disorders is a challenging
approach, especially in the case of blood withdrawal for autism spectrum disorder-affected …

[HTML][HTML] IGFBP5 is released by senescent cells and is internalized by healthy cells, promoting their senescence through interaction with retinoic receptors

…, D Aprile, G Peluso, V Mazzone, D Patrone… - Cell Communication and …, 2024 - Springer
Cells that are exposed to harmful genetic damage, either from internal or external sources,
may undergo senescence if they are unable to repair their DNA. Senescence, characterized …

Discovery of a potent inhibitor of replication protein a protein–protein interactions using a fragment-linking approach

AO Frank, MD Feldkamp, JP Kennedy… - Journal of medicinal …, 2013 - ACS Publications
Replication protein A (RPA), the major eukaryotic single-stranded DNA (ssDNA)-binding
protein, is involved in nearly all cellular DNA transactions. The RPA N-terminal domain …