Research LettersFetal HLA typing in β thalassaemia: implications for haemopoietic stem-cell transplantation
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Bone marrow transplantation for β–thalassemia: the experience of pediatric clinic in Cagliari
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Prenatal HLA-matching to determine suitability for allogeneic bone marrow transplantation
Bone Marrow Transplant
(2000)
Cited by (25)
Successful haematopoietic stem cell transplantation in 44 children from healthy siblings conceived after preimplantation HLA matching
2014, Reproductive BioMedicine OnlineCitation Excerpt :Ninety-four per cent of the transplantations used bone marrow, either alone or together with cord blood. Although, UCB cells constitute a suitable source of stem cells with high concentrations of CD34+ cells and low probability of graft failure and GVHD (Orofino et al., 2003), some problems are related to its use (Shahrokhi et al., 2012). Two reasons have been proposed to underlie these problems; first, donor T-lymphocytes may elicit a blunted allogeneic effect by the naïve immune system.
Pregnancy in patients with Cooley anemia
2012, Progresos de Obstetricia y GinecologiaSeven years of experience of preimplantation HLA typing: A clinical overview of 327 cycles
2011, Reproductive BioMedicine OnlineCitation Excerpt :HLA typing without mutation analysis has also been used for acquired diseases (Verlinsky et al., 2004), such as acute myeloid leukaemia and acute lymphoid leukaemia, which require allogenic haemopoietic stem cell transplantation (HSCT) from an HLA-identical donor for the cure of the disease. Stem cells in the cord blood from an HLA-identical sibling can be used with a much higher success rate than a transplant from alternative donors (Gaziev et al., 2000; Orofino et al., 2003) and are therefore of great therapeutic value for haematopoietic and other life-threatening diseases (Fiorentino et al., 2006; Kahraman et al., 2004, 2007; Van de Velde et al., 2004, 2009; Verlinsky et al., 2001, 2004). The selection of embryos for HLA typing necessitates the application of assisted reproduction treatment even though the vast majority of the couples are fertile.
Hemoglobinopathies in pregnancy
2004, Obstetrics and Gynecology Clinics of North AmericaCurrent Status of β-Thalassemic Burden in India
2023, Hemoglobin