PaperInformed consent in European multicentre randomised clinical trials — Are patients really informed?
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Issues in informed consent
Cited by (76)
Contributory factors to the evolution of the concept and practice of informed consent in clinical research: A narrative review
2020, Contemporary Clinical Trials CommunicationsCitation Excerpt :With the benefit of contemporary research integrity frameworks, it is easy to condemn these practices, but it was not customary at the time to obtain consent from patients to use their tissue for research purposes. An anonymous survey of 60 clinicians published in 1994 revealed that only 32% asked patients to provide written consent, and 5% did not seek consent at all [43]. Another study of 484 oncologists showed that 72% felt that IC hindered the physician-patient relationship and 87% of physicians stated IC regulations was a barrier to recruitment [44].
Qualitative research to improve RCT recruitment: Issues arising in establishing research collaborations
2008, Contemporary Clinical TrialsCitation Excerpt :In Quartet, this was also related to the bureaucratic tasks involved in securing separate ethics and governance approvals and then patients' consent for another study, with the inevitably delayed onset of the collaboration. Obtaining patients' consent to participate in any research can prove difficult [6,25,28–30] — even more so when it has to be achieved twice, as was the case with Quartet and the existing RCTs. The complexity of the recruitment process necessitated expanding the original Quartet aims to include all stages of recruitment.
Telling the truth to patients with cancer: what is the truth?
2006, Lancet Oncology