Cocaine abuse among heroin addicts in Spain

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Abstract

Abuse of cocaine is becoming a major problem among heroin addicts in Spain. Between 1987 and 1988, 75% of patients admitted as inpatients for detoxification from opiate dependence had consumed cocaine during the 6 months prior to admission and 25% had abused cocaine daily or several times/week. These cocaine abusers showed more toxicologic and psychopathologic problems than opiate addicts who did not abuse cocaine. The opiate addicts who also abused cocaine had begun using illicit drugs earlier and showed a higher frequency of anti-HIV antibodies. They also had more antisocial personality disorders and persistence of depressive symptoms during opiate detoxification than heroin addicts who did not abuse cocaine. Based on these findings, we insist on the need to develop different treatments for detoxifying patients with this dual addiction.

References (24)

  • J. Cami et al.

    Monitoring cocaine epidemics in Barcelona

    Lancet

    (1987)
  • D.N. Nurco et al.

    Nonnarcotic drug use over an addiction career — A study of heroin addicts in Baltimore and New York city

    Compreh. Psychiatry

    (1988)
  • Aids Surveillance in Europe

    Quarterly report no. 24

    (1989)
  • J.H. Atkinson et al.

    Prevalence of psychiatric disorders among men infected with human immunodeficiency virus

    Arch. Gen. Psychiatry

    (1988)
  • D.V. Burns et al.

    Cognitive behavior modification of mood disorders

  • J. Cami et al.

    Cocaina: la epidemia que viene

    Med. Clin. (Barc)

    (1988)
  • L.R. Derogatis

    Symptom Checklist 90-Revised Version

    (1983)
  • R.M. Donahoe et al.

    Neuroimmunomo-dulation by opiates and other drugs of abuse: Relationship to HIV infection and AIDS

  • F.H. Gawin et al.

    Abstinence symptomatology and psychiatric diagnosis of cocaine abusers

    Arch. Gen. Psychiatry

    (1986)
  • T.W. Klein et al.

    Suppression of human and mouse lymphocyte proliferation by cocaine

  • T.R. Kosten et al.

    Cocaine abuse among opioid addicts: Demographic and diagnostic factors in treatment

    Am. J. Drug Alcohol Abuse

    (1986)
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