Numbers of participants by subcohort for informed consent items 1–5 at baseline survey and at 6 months
| Basic survey | Basic survey + genetic analysis | p value (2-tailed) comparison between subcohorts | |||||
|---|---|---|---|---|---|---|---|
| Adogawa | Shin-asahi | Takashima | Makino | 4 areas | 2 areas without genetic analysis | 2 areas with genetic analysis | |
| NS, not significant. | |||||||
| Total | 2213 | 953 | 1065 | 1130 | |||
| Men | 812 | 277 | 344 | 438 | |||
| Women | 1401 | 676 | 721 | 692 | |||
| At baseline | |||||||
| Item 1: basic survey: | |||||||
| Total (%) | 2053 (92⋅8) | 885 (92⋅9) | 938 (88⋅1) | 945 (83⋅6) | <0⋅0001 | NS | 0⋅0033 |
| Men (%) | 765 (94⋅2) | 266 (96⋅0) | 306 (89⋅0) | 372 (84⋅9) | <0⋅0001 | NS | NS |
| Women (%) | 1288 (91⋅9) | 619 (91⋅6) | 632 (87⋅7) | 573 (82⋅8) | <0⋅0001 | NS | 0⋅0107 |
| Item 2: preservation of blood samples for future use | |||||||
| Total (%) | 2038 (92⋅1) | 878 (92⋅1) | 926 (86⋅9) | 942 (83⋅4) | <0⋅0001 | NS | 0⋅0187 |
| Men (%) | 760 (93⋅6) | 266 (96⋅0) | 304 (88⋅4) | 372 (84⋅9) | <0⋅0001 | NS | NS |
| Women (%) | 1278 (91⋅2) | 612 (90⋅5) | 622 (86⋅3) | 570 (82⋅4) | <0⋅0001 | NS | NS |
| Item 3: examination of medical records and death certificate | |||||||
| Total (%) | 2025 (91⋅5) | 875 (91⋅8) | 917 (86⋅1) | 938 (83⋅0) | <0⋅0001 | NS | 0⋅0373 |
| Men (%) | 758 (93⋅3) | 264 (95⋅3) | 304 (88⋅4) | 372 (84⋅9) | <0⋅0001 | NS | NS |
| Women (%) | 1267 (90⋅4) | 611 (90⋅4) | 613 (85⋅0) | 566 (81⋅8) | <0⋅0001 | NS | NS |
| Item 4: genetic analysis | |||||||
| Total (%) | 919 (86⋅3) | 938 (83⋅0) | 0⋅0378 | ||||
| Men (%) | 304 (88⋅4) | 372 (84⋅9) | NS | ||||
| Women (%) | 615 (85⋅3) | 566 (81⋅8) | NS | ||||
| Item 5: preservation of DNA samples for future analysis | |||||||
| Total (%) | 911 (85⋅5) | 938 (83⋅0) | NS | ||||
| Men (%) | 300 (87⋅2) | 372 (84⋅9) | NS | ||||
| Women (%) | 611 (84⋅7) | 566 (81⋅8) | NS | ||||
| After 6 months | |||||||
| Item 1: basic survey | |||||||
| Total (%) | 2045 (92⋅4) | 881 (92⋅4) | 909 (85⋅4) | 941 (83⋅3) | <0⋅0001 | NS | 0⋅0059 |
| Men (%) | 764 (94⋅1) | 266 (96⋅0) | 299 (86⋅9) | 371 (84⋅7) | <0⋅0001 | NS | NS |
| Women (%) | 1281 (91⋅4) | 615 (91⋅0) | 610 (84⋅6) | 570 (82⋅4) | <0⋅0001 | NS | 0⋅0197 |
| Item 2: preservation of blood samples for future use | |||||||
| Total (%) | 2030 (91⋅7) | 874 (91⋅7) | 897 (84⋅2) | 938 (83⋅0) | <0⋅0001 | NS | 0⋅0345 |
| Men (%) | 759 (93⋅5) | 266 (96⋅0) | 297 (86⋅3) | 371 (84⋅7) | <0⋅0001 | NS | NS |
| Women (%) | 1271 (90⋅7) | 608 (89⋅9) | 600 (83⋅2) | 567 (81⋅9) | <0⋅0001 | NS | NS |
| Item 3: examination of medical records and death certificate | |||||||
| Total (%) | 2017 (91⋅1) | 871 (91⋅4) | 888 (83⋅4) | 934 (82⋅7) | <0⋅0001 | NS | NS |
| Men (%) | 757 (93⋅2) | 264 (95⋅3) | 297 (86⋅3) | 371 (84⋅7) | <0⋅0001 | NS | NS |
| Women (%) | 1260 (89⋅9) | 607 (89⋅8) | 591 (82⋅0) | 563 (81⋅4) | <0⋅0001 | NS | NS |
| Item 4: genetic analysis | |||||||
| Total (%) | 890 (83⋅6) | 934 (82⋅7) | NS | ||||
| Men (%) | 297 (86⋅3) | 371 (84⋅7) | NS | ||||
| Women (%) | 593 (82⋅2) | 563 (81⋅4) | NS | ||||
| Item 5: preservation of DNA samples for future analysis | |||||||
| Total (%) | 882 (82⋅8) | 934 (82⋅7) | NS | ||||
| Men (%) | 293 (85⋅2) | 371 (84⋅7) | NS | ||||
| Women (%) | 589 (81⋅7) | 563 (81⋅4) | NS | ||||