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Non-compliance: a side effect of drug information leaflets

Department of Legal Medicine, College of Medicine and Odontology, University of Valencia, Valencia, Spain

Correspondence to:
Dr F Verdú
Department of Legal Medicine, College of Medicine and Odontology, University of Valencia E G, Av/ Blasco Ibañez, n°15, 46010-Valencia (Spain); Fernando.Verdu@uv.es

Keywords: non-compliance; side effect; informed consent

The first 150 words of the full text of this article appear below.

The problem of non-compliance with treatment and its repercussions on the clinical evolution of different conditions has been widely investigated.^1–4 Non-compliance has also been shown to have significant economic implications, not only as a result of product loss but also indirectly through the complication of disease management and its subsequent healthcare and social costs.^5–7

Non-compliance as a health problem
The term "non-compliance" might be taken to refer both to the failure to follow a drug regimen and to the failure to adopt other measures that contribute to improvement in health—for example, changes in lifestyle or diet. This letter focuses on the former.

Non-compliance with a drug regimen can be the result of a number of different factors^9–11 and a variety of techniques have been developed in an attempt to control it.^12,13 Of these, the few techniques that have been shown to be effective have only managed to solve the problem in specific situations over short . . . [Full text of this article]