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Journal of Medical Ethics 2001;27:177-178; doi:10.1136/jme.27.3.177
Copyright © 2001 by the BMJ Publishing Group Ltd & Institute of Medical Ethics.
J Med Ethics 2001; 27:177-178
© 2001 the Journal of Medical Ethics

At the coalface: medical ethics in practice

Randomised clinical trials: a source of ethical dilemmas

Fernando Verdú-Pascual and Ana Castelló-Ponce

University of Valencia, Spain

Abstract

Advances in medicine are closely linked to clinical research, but certain study procedures may be in conflict with the fundamental principles of ethics and codes of conduct in medicine. Following an analysis of two studies involving treatments for acute myocardial infarction (AMI), the admissibility of continuing a study was questioned after the initial results for two types of treatment showed that one was significantly better than the other. Also considered doubtful was the information provided to patients with the object of obtaining their informed consent.

Key Words: Clinical trial • randomisation • medical ethics


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This article has been cited by other articles:

  • Hilden, J, Gammelgaard, A (2002). Premature stopping and informed consent in AMI trials. J. Med. Ethics 28: 188-189 [Abstract] [Full Text]  

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